Endothelial Nitric Oxide Synthase (−786T>C) and Endothelin-1 (5665G>T) Gene Polymorphisms as Vascular Dysfunction Risk Factors in Sickle Cell Anemia

Sickle cell anemia (SCA) patients have vascular complications, and polymorphisms in endothelin-1 (ET-1) and endothelial nitric oxide synthase (eNOS) genes were associated with ET-1 and nitric oxide disturbance. We investigate the association of ET-1 5665G>T and eNOS −786T>C polymorphisms with...

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Veröffentlicht in:Gene Regul Syst Bio
Hauptverfasser: Vilas-Boas, Wendell, Figueiredo, Camylla V. B., Pitanga, Thassila N., Carvalho, Magda O. S., Santiago, Rayra P., Santana, Sânzio S., Guarda, Caroline C., Zanette, Angela M. D., Cerqueira, Bruno A. V., Gonçalves, Marilda S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Libertas Academica 2016
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966487/
https://ncbi.nlm.nih.gov/pubmed/27486304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/GRSB.S38276
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