A potent neutralizing IgM mAb targeting the N218 epitope on E2 protein protects against Chikungunya virus pathogenesis

Chikungunya virus (CHIKV) is a medically important human viral pathogen that causes Chikungunya fever accompanied with debilitating and persistent joint pain. Host-elicited or passively-transferred monoclonal antibodies (mAb) are essential mediators of CHIKV clearance. Therefore, this study aimed to...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Lam, Shirley, Nyo, Min, Phuektes, Patchara, Yew, Chow Wenn, Tan, Yee Joo, Chu, Justin Jang Hann
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966480/
https://ncbi.nlm.nih.gov/pubmed/26305993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1083664
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