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IRF3 promotes adipose inflammation and insulin resistance and represses browning
The chronic inflammatory state that accompanies obesity is a major contributor to insulin resistance and other dysfunctional adaptations in adipose tissue. Cellular and secreted factors promote the inflammatory milieu of obesity, but the transcriptional pathways that drive these processes are not we...
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| Опубликовано в: : | J Clin Invest |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4966307/ https://ncbi.nlm.nih.gov/pubmed/27400129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI86080 |
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