Developmental SHP2 dysfunction underlies cardiac hypertrophy in Noonan syndrome with multiple lentigines

Hypertrophic cardiomyopathy is a common cause of mortality in congenital heart disease (CHD). Many gene abnormalities are associated with cardiac hypertrophy, but their function in cardiac development is not well understood. Loss-of-function mutations in PTPN11, which encodes the protein tyrosine ph...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:J Clin Invest
Main Authors: Lauriol, Jessica, Cabrera, Janel R., Roy, Ashbeel, Keith, Kimberly, Hough, Sara M., Damilano, Federico, Wang, Bonnie, Segarra, Gabriel C., Flessa, Meaghan E., Miller, Lauren E., Das, Saumya, Bronson, Roderick, Lee, Kyu-Ho, Kontaridis, Maria I.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2016
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966304/
https://ncbi.nlm.nih.gov/pubmed/27348588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80396
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla