Study of the function of G-rich aptamers selected for lung adenocarcinoma

G-rich oligonucleotides have attracted considerable interest as therapeutic agents. In this report, we tested two G-rich aptamers selected against EGFR-transfected A549 cells, and their G-rich domains (S13 and S50) were identified to account for the binding of parental aptamers. CD spectra showed th...

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Bibliografiske detaljer
Udgivet i:Chem Asian J
Main Authors: Hu, Jun, Zhao, Zilong, Liu, Qiaoling, Ye, Mao, Hu, Bingqiang, Wang, Jing, Tan, Weihong
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4966285/
https://ncbi.nlm.nih.gov/pubmed/25864879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/asia.201500187
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