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Generating Aptamers by Cell-SELEX for Applications in Molecular Medicine
Aptamers are single-stranded oligonucleotides of DNA or RNA that bind to target molecules with high affinity and specificity. Typically, aptamers are generated by an iterative selection process, called systematic evolution of ligands by exponential enrichment (SELEX). Recent advancements in SELEX te...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Molecular Diversity Preservation International (MDPI)
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3317715/ https://ncbi.nlm.nih.gov/pubmed/22489154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13033341 |
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