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Generating Aptamers by Cell-SELEX for Applications in Molecular Medicine

Aptamers are single-stranded oligonucleotides of DNA or RNA that bind to target molecules with high affinity and specificity. Typically, aptamers are generated by an iterative selection process, called systematic evolution of ligands by exponential enrichment (SELEX). Recent advancements in SELEX te...

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Autors principals: Ye, Mao, Hu, Jun, Peng, Minyuan, Liu, Jing, Liu, Jun, Liu, Huixia, Zhao, Xielan, Tan, Weihong
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International (MDPI) 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317715/
https://ncbi.nlm.nih.gov/pubmed/22489154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13033341
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