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Generating Aptamers by Cell-SELEX for Applications in Molecular Medicine

Aptamers are single-stranded oligonucleotides of DNA or RNA that bind to target molecules with high affinity and specificity. Typically, aptamers are generated by an iterative selection process, called systematic evolution of ligands by exponential enrichment (SELEX). Recent advancements in SELEX te...

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Detalhes bibliográficos
Main Authors: Ye, Mao, Hu, Jun, Peng, Minyuan, Liu, Jing, Liu, Jun, Liu, Huixia, Zhao, Xielan, Tan, Weihong
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3317715/
https://ncbi.nlm.nih.gov/pubmed/22489154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13033341
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