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Pervasive isoform‐specific translational regulation via alternative transcription start sites in mammals

Transcription initiated at alternative sites can produce mRNA isoforms with different 5ʹUTRs, which are potentially subjected to differential translational regulation. However, the prevalence of such isoform‐specific translational control across mammalian genomes is currently unknown. By combining p...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Syst Biol
Main Authors: Wang, Xi, Hou, Jingyi, Quedenau, Claudia, Chen, Wei
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965872/
https://ncbi.nlm.nih.gov/pubmed/27430939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20166941
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