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Alternative transcription start site selection leads to large differences in translation activity in yeast
mRNA levels do not accurately predict protein levels in eukaryotic cells. To investigate contributions of 5′ untranslated regions (5′ UTRs) to mRNA-specific differences in translation, we determined the 5′ UTR boundaries of 96 yeast genes for which in vivo translational efficiency varied by 80-fold....
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3504680/ https://ncbi.nlm.nih.gov/pubmed/23105001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.035865.112 |
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