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SNP and indel frequencies at transcription start sites and at canonical and alternative translation initiation sites in the human genome

Single-nucleotide polymorphisms (SNPs) are the most common form of genetic variation in humans and drive phenotypic variation. Due to evolutionary conservation, SNPs and indels (insertion and deletions) are depleted in functionally important sequence elements. Recently, population-scale sequencing e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Neininger, Kerstin, Marschall, Tobias, Helms, Volkhard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461226/
https://ncbi.nlm.nih.gov/pubmed/30978217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214816
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