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In Vivo Bioorthogonal Chemistry Enables Local Hydrogel and Systemic Pro-Drug To Treat Soft Tissue Sarcoma
[Image: see text] The ability to activate drugs only at desired locations avoiding systemic immunosuppression and other dose limiting toxicities is highly desirable. Here we present a new approach, named local drug activation, that uses bioorthogonal chemistry to concentrate and activate systemic sm...
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| Publicado no: | ACS Cent Sci |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2016
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4965853/ https://ncbi.nlm.nih.gov/pubmed/27504494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.6b00150 |
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