Activation of Epidermal Growth Factor Receptor/p38/Hypoxia-inducible Factor-1α Is Pivotal for Angiogenesis and Tumorigenesis of Malignantly Transformed Cells Induced by Hexavalent Chromium

Hexavalent chromium (Cr(VI))-containing compounds are well established environmental carcinogens. Most mechanistic investigations of Cr(VI)-induced carcinogenesis focus on oxidative stress and various cellular responses, leading to malignant cell transformation or the first stage of metal-induced ca...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kim, Donghern, Dai, Jin, Park, Youn-hee, Fai, Leonard Yenwong, Wang, Lei, Pratheeshkumar, Poyil, Son, Young-Ok, Kondo, Kazuya, Xu, Mei, Luo, Jia, Shi, Xianglin, Zhang, Zhuo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965575/
https://ncbi.nlm.nih.gov/pubmed/27226640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.715797
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