Loss of fructose-1,6-bisphosphatase induces glycolysis and promotes apoptosis resistance of cancer stem-like cells: an important role in hexavalent chromium-induced carcinogenesis

Hexavalent chromium (Cr(VI)) compounds are confirmed human carcinogens for lung cancer. Our previous studies has demonstrated that chronic exposure of human bronchial epithelial BEAS-2B cells to low dose of Cr(VI) causes malignant cell transformation. The acquisition of cancer stem cell-like propert...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Dai, Jin, Ji, Yanli, Wang, Wei, Kim, Donghern, Fai, Leonard Yenwong, Wang, Lei, Luo, Jia, Zhang, Zhuo
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567692/
https://ncbi.nlm.nih.gov/pubmed/28624442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2017.06.014
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