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Potentiation of DNA adduct formation in HL-60 cells by combinations of benzene metabolites.

Using P1 nuclease enhanced 32P postlabeling, we investigated DNA adduct formation in HL-60 promyelocytic leukemia cells treated with the benzene metabolites hydroquinone, catechol, and 1,2,4-benzenetriol. Comparison of the slopes of the dose-response curves showed that hydroquinone was 7-9 times mor...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lévay, G, Bodell, W J
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1992
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49654/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1496006/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.15.7105
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