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Deletion of Angiotensin II Type 2 Receptor Accelerates Adipogenesis in Murine Mesenchymal Stem Cells via Wnt10b/beta-catenin Signaling

Recent evidence suggests that the renin-angiotensin system (RAS) plays a vital role in adipocyte biology and the pathophysiology of metabolic syndrome. Obesity is the main culprit of metabolic syndrome and mesenchymal stem cells (MSCs) have been forwarded as a major source of adipocyte generation. P...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Matsushita, Kenichi, Wu, Yaojiong, Pratt, Richard E, Dzau, Victor J
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965305/
https://ncbi.nlm.nih.gov/pubmed/27295344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2016.66
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