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The roles of the conserved tyrosine in the β2-α2 loop of the prion protein

Prions cause neurodegenerative diseases for which no cure exists. Despite decades of research activities the function of the prion protein (PrP) in mammalians is not known. Moreover, little is known on the molecular mechanisms of the self-assembly of the PrP from its monomeric state (cellular PrP, P...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Prion
Hauptverfasser: Huang, Danzhi, Caflisch, Amedeo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964861/
https://ncbi.nlm.nih.gov/pubmed/26689486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1115944
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