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The roles of the conserved tyrosine in the β2-α2 loop of the prion protein

Prions cause neurodegenerative diseases for which no cure exists. Despite decades of research activities the function of the prion protein (PrP) in mammalians is not known. Moreover, little is known on the molecular mechanisms of the self-assembly of the PrP from its monomeric state (cellular PrP, P...

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Detalhes bibliográficos
Publicado no:Prion
Main Authors: Huang, Danzhi, Caflisch, Amedeo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964861/
https://ncbi.nlm.nih.gov/pubmed/26689486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2015.1115944
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