Generation of human MHC (HLA-A11/DR1) transgenic mice for vaccine evaluation

The rapid occurrence of emerging infectious diseases demonstrates an urgent need for a new preclinical experimental model that reliably replicates human immune responses. Here, a new homozygous humanized human leukocyte antigen (HLA)-A11/DR1 transgenic mouse (HLA-A11(+/+)/DR01(+/+)/H-2-β(2m)(−/−)/IA...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Zeng, Yang, Gao, Tongtong, Zhao, Guangyu, Jiang, Yuting, Yang, Yi, Yu, Hong, Kou, Zhihua, Lone, Yuchun, Sun, Shihui, Zhou, Yusen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964720/
https://ncbi.nlm.nih.gov/pubmed/26479036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1103405
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