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Exome-based Variant Detection in Core Promoters

Core promoter controls the initiation of transcription. Core promoter sequence change can disrupt transcriptional regulation, lead to impairment of gene expression and ultimately diseases. Therefore, comprehensive characterization of core promoters is essential to understand normal and abnormal gene...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kim, Yeong C., Cui, Jian, Luo, Jiangtao, Xiao, Fengxia, Downs, Bradley, Wang, San Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964598/
https://ncbi.nlm.nih.gov/pubmed/27464681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30716
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