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Engineering Salmonella as intracellular factory for effective killing of tumour cells

Salmonella have many desirable properties as antitumour-agent due to its ability to proliferate inside tumours and induce tumour regression. Additionally, this bacterium can be genetically engineered to deliver therapeutic proteins intratumourally. The main limitation of this approach is the efficie...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Camacho, Eva María, Mesa-Pereira, Beatriz, Medina, Carlos, Flores, Amando, Santero, Eduardo
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964584/
https://ncbi.nlm.nih.gov/pubmed/27464652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30591
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