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Engineering Salmonella as intracellular factory for effective killing of tumour cells
Salmonella have many desirable properties as antitumour-agent due to its ability to proliferate inside tumours and induce tumour regression. Additionally, this bacterium can be genetically engineered to deliver therapeutic proteins intratumourally. The main limitation of this approach is the efficie...
Gardado en:
| Publicado en: | Sci Rep |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4964584/ https://ncbi.nlm.nih.gov/pubmed/27464652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30591 |
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