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Engineering Salmonella as intracellular factory for effective killing of tumour cells

Salmonella have many desirable properties as antitumour-agent due to its ability to proliferate inside tumours and induce tumour regression. Additionally, this bacterium can be genetically engineered to deliver therapeutic proteins intratumourally. The main limitation of this approach is the efficie...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Camacho, Eva María, Mesa-Pereira, Beatriz, Medina, Carlos, Flores, Amando, Santero, Eduardo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964584/
https://ncbi.nlm.nih.gov/pubmed/27464652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30591
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