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Engineering Salmonella as intracellular factory for effective killing of tumour cells

Salmonella have many desirable properties as antitumour-agent due to its ability to proliferate inside tumours and induce tumour regression. Additionally, this bacterium can be genetically engineered to deliver therapeutic proteins intratumourally. The main limitation of this approach is the efficie...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Camacho, Eva María, Mesa-Pereira, Beatriz, Medina, Carlos, Flores, Amando, Santero, Eduardo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964584/
https://ncbi.nlm.nih.gov/pubmed/27464652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30591
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