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Allelic Variation of the Capsule Promoter Diversifies Encapsulation and Virulence In Streptococcus pneumoniae

The polysaccharide capsule is the major virulence factor of Streptococcus pneumoniae (pneumococcus), a major human pathogen. The sequences in the promoter and coding regions of the capsule gene locus undergo extensive variations through the natural transformation-mediated horizontal gene transfer. T...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Wen, Zhensong, Liu, Yanni, Qu, Fen, Zhang, Jing-Ren
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964562/
https://ncbi.nlm.nih.gov/pubmed/27465908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30176
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