The Streptococcus pneumoniae Capsule Is Required for Full Virulence in Pneumococcal Endophthalmitis

PURPOSE. To determine whether Streptococcus pneumoniae capsule was necessary for pathogenesis of pneumococcal endophthalmitis. METHODS. An isogenic capsule-deficient strain was created using homologous recombination. New Zealand White rabbits were injected intravitreously with 10(2) colony-forming u...

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Bibliographic Details
Main Authors: Sanders, Melissa E., Norcross, Erin W., Robertson, Zachary M., Moore, Quincy C., Fratkin, Jonathan, Marquart, Mary E.
Format: Artigo
Language:Inglês
Published: Association for Research in Vision and Ophthalmology, Inc. 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053111/
https://ncbi.nlm.nih.gov/pubmed/21051708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5513
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