Deletion of arcD in Streptococcus pneumoniae D39 Impairs Its Capsule and Attenuates Virulence

The arginine deiminase system (ADS) is associated with arginine catabolism and plays a role in virulence of several pathogenic bacteria. In Streptococcus pneumoniae, the ADS genes exist as a locus consisting of arcABCDT. A recent genome-wide mutagenesis approach revealed that both arcD and arcT are...

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Main Authors: Gupta, Radha, Yang, Jun, Dong, Yimin, Swiatlo, Edwin, Zhang, Jing-Ren, Metzger, Dennis W., Bai, Guangchun
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2013
主題:
Molecular Pathogenesis
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811789/
https://ncbi.nlm.nih.gov/pubmed/23918778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00778-13
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