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Niemann-Pick Type C2 Protein Mediates Hepatic Stellate Cells Activation by Regulating Free Cholesterol Accumulation

In chronic liver diseases, regardless of their etiology, the development of fibrosis is the first step toward the progression to cirrhosis, portal hypertension, and hepatocellular carcinoma. Hepatic stellate cells (HSCs) are the main profibrogenic cells that promote the pathogenesis of liver fibrosi...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Twu, Yuh-Ching, Lee, Tzong-Shyuan, Lin, Yun-Lian, Hsu, Shih-Ming, Wang, Yuan-Hsi, Liao, Chia-Yu, Wang, Chung-Kwe, Liang, Yu-Chih, Liao, Yi-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964497/
https://ncbi.nlm.nih.gov/pubmed/27420058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17071122
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