Glycine N-Methyltransferase Deficiency Affects Niemann-Pick Type C2 Protein Stability and Regulates Hepatic Cholesterol Homeostasis

Nonalcoholic fatty liver disease (NAFLD) is associated with the development of metabolic syndromes and hepatocellular carcinoma (HCC). Cholesterol accumulation is related to NAFLD, whereas its detailed mechanism is not fully understood. Previously, we reported that glycine N-methyltransferase (GNMT)...

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Autors principals: Liao, Yi-Jen, Chen, Tzu-Lang, Lee, Tzong-Shyuan, Wang, Hsiang-An, Wang, Chung-Kwe, Liao, Li-Ying, Liu, Ren-Shyan, Huang, Shiu-Feng, Chen, Yi-Ming Arthur
Format: Artigo
Idioma:Inglês
Publicat: ScholarOne 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356423/
https://ncbi.nlm.nih.gov/pubmed/22183894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2011.00258
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