Hypoxia Potentiates Anabolic Effects of Exogenous Hyaluronic Acid in Rat Articular Cartilage

Hyaluronic acid (HA) is used clinically to treat osteoarthritis (OA), but its pharmacological effects under hypoxic conditions remain unclear. Articular chondrocytes in patients with OA are exposed to a hypoxic environment. This study investigated whether hypoxia could potentiate the anabolic effect...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ichimaru, Shohei, Nakagawa, Shuji, Arai, Yuji, Kishida, Tsunao, Shin-Ya, Masaharu, Honjo, Kuniaki, Tsuchida, Shinji, Inoue, Hiroaki, Fujiwara, Hiroyoshi, Shimomura, Seiji, Mazda, Osam, Kubo, Toshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964389/
https://ncbi.nlm.nih.gov/pubmed/27347945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17071013
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