Suppression of heat shock protein 70 by siRNA enhances the antitumor effects of cisplatin in cultured human osteosarcoma cells

Although advances in chemotherapy have improved the prognosis for osteosarcoma, some patients do not respond sufficiently to treatment. Heat shock protein 70 (Hsp70) is expressed at high levels in cancer cells and attenuates the therapeutic efficacy of anticancer agents, resulting in a poorer progno...

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Bibliografische gegevens
Gepubliceerd in:Cell Stress Chaperones
Hoofdauteurs: Mori, Yuki, Terauchi, Ryu, Shirai, Toshiharu, Tsuchida, Shinji, Mizoshiri, Naoki, Arai, Yuji, Kishida, Tsunao, Fujiwara, Hiroyoshi, Mazda, Osam, Kubo, Toshikazu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Netherlands 2017
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Original Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573688/
https://ncbi.nlm.nih.gov/pubmed/28466152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0793-x
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