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Suppression of heat shock protein 70 by siRNA enhances the antitumor effects of cisplatin in cultured human osteosarcoma cells

Although advances in chemotherapy have improved the prognosis for osteosarcoma, some patients do not respond sufficiently to treatment. Heat shock protein 70 (Hsp70) is expressed at high levels in cancer cells and attenuates the therapeutic efficacy of anticancer agents, resulting in a poorer progno...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Mori, Yuki, Terauchi, Ryu, Shirai, Toshiharu, Tsuchida, Shinji, Mizoshiri, Naoki, Arai, Yuji, Kishida, Tsunao, Fujiwara, Hiroyoshi, Mazda, Osam, Kubo, Toshikazu
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573688/
https://ncbi.nlm.nih.gov/pubmed/28466152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0793-x
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