A phase I, placebo-controlled, randomized, double-blind, single ascending dose-ranging study to evaluate the safety and tolerability of a novel biophysical bronchodilator (S-1226) administered by nebulization in healthy volunteers

BACKGROUND: A major challenge in treating acute asthma exacerbations is the need to open constricted airways rapidly enough to reestablish ventilation and allow delivery of conventional medication to diseased airways. The solution requires a new approach that considers both biophysical and pharmacol...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Trials
Autori principali: Green, Francis H. Y., Leigh, Richard, Fadayomi, Morenike, Lalli, Gurkeet, Chiu, Andrea, Shrestha, Grishma, ElShahat, Sharif G., Nelson, David Evan, El Mays, Tamer Y., Pieron, Cora A., Dennis, John H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964056/
https://ncbi.nlm.nih.gov/pubmed/27464582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-016-1489-8
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