A phase I, placebo-controlled, randomized, double-blind, single ascending dose-ranging study to evaluate the safety and tolerability of a novel biophysical bronchodilator (S-1226) administered by nebulization in healthy volunteers

BACKGROUND: A major challenge in treating acute asthma exacerbations is the need to open constricted airways rapidly enough to reestablish ventilation and allow delivery of conventional medication to diseased airways. The solution requires a new approach that considers both biophysical and pharmacol...

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Опубликовано в: :Trials
Главные авторы: Green, Francis H. Y., Leigh, Richard, Fadayomi, Morenike, Lalli, Gurkeet, Chiu, Andrea, Shrestha, Grishma, ElShahat, Sharif G., Nelson, David Evan, El Mays, Tamer Y., Pieron, Cora A., Dennis, John H.
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2016
Предметы:
Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964056/
https://ncbi.nlm.nih.gov/pubmed/27464582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-016-1489-8
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