A phase I, placebo-controlled, randomized, double-blind, single ascending dose-ranging study to evaluate the safety and tolerability of a novel biophysical bronchodilator (S-1226) administered by nebulization in healthy volunteers

BACKGROUND: A major challenge in treating acute asthma exacerbations is the need to open constricted airways rapidly enough to reestablish ventilation and allow delivery of conventional medication to diseased airways. The solution requires a new approach that considers both biophysical and pharmacol...

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Detalhes bibliográficos
Publicado no:Trials
Main Authors: Green, Francis H. Y., Leigh, Richard, Fadayomi, Morenike, Lalli, Gurkeet, Chiu, Andrea, Shrestha, Grishma, ElShahat, Sharif G., Nelson, David Evan, El Mays, Tamer Y., Pieron, Cora A., Dennis, John H.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964056/
https://ncbi.nlm.nih.gov/pubmed/27464582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-016-1489-8
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