Protein tyrosine phosphatase 1B negatively regulates S100A9-mediated lung damage during respiratory syncytial virus exacerbations

Protein tyrosine phosphatase 1B (PTP1B) has anti-inflammatory potential but PTP1B responses are desensitized in the lung by prolonged cigarette smoke exposure. Here we investigate whether PTP1B expression impacts lung disease severity during respiratory syncytial viral (RSV) exacerbations of chronic...

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Gepubliceerd in:Mucosal Immunol
Hoofdauteurs: Foronjy, Robert F., Ochieng, Pius O., Salathe, Matthias A., Dabo, Abdoulaye J., Eden, Edward, Baumlin, Nathalie, Cummins, Neville, Barik, Sailen, Campos, Michael, Thorp, Edward B., Geraghty, Patrick
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963308/
https://ncbi.nlm.nih.gov/pubmed/26813343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.138
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