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TLR9 expression is required for the development of cigarette smoke-induced emphysema in mice

The expression of Toll-like receptor (TLR)-9, a pathogen recognition receptor that recognizes unmethylated CpG sequences in microbial DNA molecules, is linked to the pathogenesis of several lung diseases. TLR9 expression and signaling was investigated in animal and cell models of chronic obstructive...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Foronjy, Robert F., Salathe, Matthias A., Dabo, Abdoulaye J., Baumlin, Nathalie, Cummins, Neville, Eden, Edward, Geraghty, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4967186/
https://ncbi.nlm.nih.gov/pubmed/27288485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00073.2016
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