Protein tyrosine phosphatase 1B negatively regulates S100A9-mediated lung damage during respiratory syncytial virus exacerbations

Protein tyrosine phosphatase 1B (PTP1B) has anti-inflammatory potential but PTP1B responses are desensitized in the lung by prolonged cigarette smoke exposure. Here we investigate whether PTP1B expression impacts lung disease severity during respiratory syncytial viral (RSV) exacerbations of chronic...

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Veröffentlicht in:Mucosal Immunol
Hauptverfasser: Foronjy, Robert F., Ochieng, Pius O., Salathe, Matthias A., Dabo, Abdoulaye J., Eden, Edward, Baumlin, Nathalie, Cummins, Neville, Barik, Sailen, Campos, Michael, Thorp, Edward B., Geraghty, Patrick
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963308/
https://ncbi.nlm.nih.gov/pubmed/26813343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.138
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