Glucocorticoid receptor-PPARα axis in fetal mouse liver prepares neonates for milk lipid catabolism

In mammals, hepatic lipid catabolism is essential for the newborns to efficiently use milk fat as an energy source. However, it is unclear how this critical trait is acquired and regulated. We demonstrate that under the control of PPARα, the genes required for lipid catabolism are transcribed before...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Rando, Gianpaolo, Tan, Chek Kun, Khaled, Nourhène, Montagner, Alexandra, Leuenberger, Nicolas, Bertrand-Michel, Justine, Paramalingam, Eeswari, Guillou, Hervé, Wahli, Walter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2016
Konular:
Developmental Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963200/
https://ncbi.nlm.nih.gov/pubmed/27367842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.11853
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