A single kinase generates the majority of the secreted phosphoproteome

The existence of extracellular phosphoproteins has been acknowledged for over a century. However, research in this area has been undeveloped largely because the kinases that phosphorylate secreted proteins have escaped identification. Fam20C is a kinase that phosphorylates S-x-E/pS motifs on protein...

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Veröffentlicht in:Cell
Hauptverfasser: Tagliabracci, Vincent S., Wiley, Sandra E., Guo, Xiao, Kinch, Lisa N., Durrant, Eric, Wen, Jianzhong, Xiao, Junyu, Cui, Jixin, Nguyen, Kim B., Engel, James L., Coon, Joshua J., Grishin, Nick, Pinna, Lorenzo A., Pagliarini, David J., Dixon, Jack E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963185/
https://ncbi.nlm.nih.gov/pubmed/26091039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.028
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