A single kinase generates the majority of the secreted phosphoproteome

The existence of extracellular phosphoproteins has been acknowledged for over a century. However, research in this area has been undeveloped largely because the kinases that phosphorylate secreted proteins have escaped identification. Fam20C is a kinase that phosphorylates S-x-E/pS motifs on protein...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Tagliabracci, Vincent S., Wiley, Sandra E., Guo, Xiao, Kinch, Lisa N., Durrant, Eric, Wen, Jianzhong, Xiao, Junyu, Cui, Jixin, Nguyen, Kim B., Engel, James L., Coon, Joshua J., Grishin, Nick, Pinna, Lorenzo A., Pagliarini, David J., Dixon, Jack E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963185/
https://ncbi.nlm.nih.gov/pubmed/26091039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.05.028
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