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Induction of protective neutralizing antibody responses against botulinum neurotoxin serotype C using plasmid carried by PLGA nanoparticles

Botulinum neurotoxin (BoNT) is a lethal neurotoxin, for which there is currently not an approved vaccine. Recent efforts in developing vaccine candidates against botulism have been directed at the heavy chain fragment of BoNT, because antibodies against this region have been shown to prevent BoNT fr...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Ruwona, Tinashe B., Xu, Haiyue, Li, Junwei, Diaz-Arévalo, Diana, Kumar, Amit, Zeng, Mingtao, Cui, Zhengrong
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4963044/
https://ncbi.nlm.nih.gov/pubmed/26837242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2015.1122147
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