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The Role of gsp Mutations on the Development of Adrenocortical Tumors and Adrenal Hyperplasia

Somatic GNAS point mutations, commonly known as gsp mutations, are involved in the pathogenesis of McCune–Albright syndrome (MAS) and have also been described in autonomous hormone-producing tumors, such as somatotropinoma, corticotrophoma, thyroid cancer, ovarian and testicular Leydig cell tumors,...

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Veröffentlicht in:Front Endocrinol (Lausanne)
Hauptverfasser: Villares Fragoso, Maria Candida Barisson, Wanichi, Ingrid Quevedo, Cavalcante, Isadora Pontes, Mariani, Beatriz Marinho de Paula
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962502/
https://ncbi.nlm.nih.gov/pubmed/27512387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2016.00104
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