Amplification of the Insulin-Like Growth Factor 1 Receptor Gene Is a Rare Event in Adrenocortical Adenocarcinomas: Searching for Potential Mechanisms of Overexpression

Context. IGF1R overexpression appears to be a prognostic biomarker of metastatic pediatric adrenocortical tumors. However, the molecular mechanisms that are implicated in its upregulation remain unknown. Aim. To investigate the potential mechanisms involved in IGF1R overexpression. Patients and Meth...

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Main Authors: Ribeiro, Tamaya Castro, Jorge, Alexander Augusto, Almeida, Madson Q., Mariani, Beatriz Marinho de Paula, Nishi, Mirian Yumi, Mendonca, Berenice Bilharinho, Fragoso, Maria Candida Barisson Villares, Latronico, Ana Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4119736/
https://ncbi.nlm.nih.gov/pubmed/25110710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/936031
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