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The Role of gsp Mutations on the Development of Adrenocortical Tumors and Adrenal Hyperplasia

Somatic GNAS point mutations, commonly known as gsp mutations, are involved in the pathogenesis of McCune–Albright syndrome (MAS) and have also been described in autonomous hormone-producing tumors, such as somatotropinoma, corticotrophoma, thyroid cancer, ovarian and testicular Leydig cell tumors,...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Villares Fragoso, Maria Candida Barisson, Wanichi, Ingrid Quevedo, Cavalcante, Isadora Pontes, Mariani, Beatriz Marinho de Paula
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962502/
https://ncbi.nlm.nih.gov/pubmed/27512387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2016.00104
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