Efficient TALEN-mediated myostatin gene editing in goats

BACKGROUND: Myostatin (MSTN) encodes a negative regulator of skeletal muscle mass that might have applications for promoting muscle growth in livestock. In this study, we aimed to test whether targeted MSTN editing, mediated by transcription activator-like effector nucleases (TALENs), is a viable ap...

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Detalles Bibliográficos
Publicado en:BMC Dev Biol
Main Authors: Yu, Baoli, Lu, Rui, Yuan, Yuguo, Zhang, Ting, Song, Shaozheng, Qi, Zhengqiang, Shao, Bin, Zhu, Mengmin, Mi, Fei, Cheng, Yong
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962387/
https://ncbi.nlm.nih.gov/pubmed/27461387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12861-016-0126-9
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