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A cholesterol-binding domain in STIM1 modulates STIM1-Orai1 physical and functional interactions
STIM1 and Orai1 are the main components of a widely conserved Calcium influx pathway known as store-operated calcium entry (SOCE). STIM1 is a calcium sensor, which oligomerizes and activates Orai channels when calcium levels drop inside the endoplasmic reticulum (ER). The series of molecular rearran...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4962086/ https://ncbi.nlm.nih.gov/pubmed/27459950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29634 |
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