The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration

Protease nexin-1 (PN-1) is a serine protease inhibitor belonging to the serpin superfamily. This study was undertaken to investigate the regulatory role of PN-1 in the pathogenesis of intervertebral disk (IVD) degeneration. Expression of PN-1 was detected in human IVD tissue of varying grades. Expre...

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Опубликовано в: :Sci Rep
Главные авторы: Wu, Xinghuo, Liu, Wei, Duan, Zhenfeng, Gao, Yong, Li, Shuai, Wang, Kun, Song, Yu, Shao, Zengwu, Yang, Shuhua, Yang, Cao
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962060/
https://ncbi.nlm.nih.gov/pubmed/27460424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30563
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