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Therapeutic Targeting of Telomerase

Telomere length and cell function can be preserved by the human reverse transcriptase telomerase (hTERT), which synthesizes the new telomeric DNA from a RNA template, but is normally restricted to cells needing a high proliferative capacity, such as stem cells. Consequently, telomerase-based therapi...

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Bibliografiske detaljer
Udgivet i:Genes (Basel)
Main Authors: Jäger, Kathrin, Walter, Michael
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4962009/
https://ncbi.nlm.nih.gov/pubmed/27455328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes7070039
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