SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein

Proteolytic generation of amyloidogenic amyloid β (Aβ) fragments from the amyloid precursor protein (APP) significantly contributes to Alzheimer's disease (AD). Although amyloidogenic APP proteolysis can be affected by trafficking through genetically associated AD components such as SORLA, how...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Huang, Timothy Y., Zhao, Yingjun, Li, Xiaoguang, Wang, Xin, Tseng, I-Chu, Thompson, Robert, Tu, Shichun, Willnow, Thomas E., Zhang, Yun-wu, Xu, Huaxi
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2016
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961782/
https://ncbi.nlm.nih.gov/pubmed/27466343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0206-16.2016
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker