SNX27 and SORLA Interact to Reduce Amyloidogenic Subcellular Distribution and Processing of Amyloid Precursor Protein

Proteolytic generation of amyloidogenic amyloid β (Aβ) fragments from the amyloid precursor protein (APP) significantly contributes to Alzheimer's disease (AD). Although amyloidogenic APP proteolysis can be affected by trafficking through genetically associated AD components such as SORLA, how...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Huang, Timothy Y., Zhao, Yingjun, Li, Xiaoguang, Wang, Xin, Tseng, I-Chu, Thompson, Robert, Tu, Shichun, Willnow, Thomas E., Zhang, Yun-wu, Xu, Huaxi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2016
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961782/
https://ncbi.nlm.nih.gov/pubmed/27466343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0206-16.2016
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