The Alarmin HMGB1 Mediates Age-Induced Neuroinflammatory Priming

Amplified neuroinflammatory responses following an immune challenge occur with normal aging and can elicit or exacerbate neuropathology. The mechanisms mediating this sensitized or “primed” immune response in the aged brain are not fully understood. The alarmin high mobility group box 1 (HMGB1) can...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Fonken, Laura K., Frank, Matthew G., Kitt, Meagan M., D'Angelo, Heather M., Norden, Diana M., Weber, Michael D., Barrientos, Ruth M., Godbout, Jonathan P., Watkins, Linda R., Maier, Steven F.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2016
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4961779/
https://ncbi.nlm.nih.gov/pubmed/27466339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1161-16.2016
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