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Promotion of Pro-Apoptotic Signals by Lysosomal Photodamage: Mechanistic Aspects and Influence of Autophagy
Prior studies demonstrated that a low level (LD(10–15)) of lysosomal photodamage can sensitize cells to the apoptotic death that results from subsequent mitochondrial photodamage. We have proposed that this process occurs via a calpain-catalyzed cleavage of the autophagy-associated protein ATG5 to f...
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| Veröffentlicht in: | Photochem Photobiol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4961560/ https://ncbi.nlm.nih.gov/pubmed/27096545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/php.12592 |
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