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Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves bid cleavage

Photodynamic therapy (PDT) protocols employing lysosomal sensitizers induce apoptosis via a mechanism that causes cytochrome c release prior to loss of mitochondrial membrane potential (ΔΨ(m)). The current study was designed to determine how lysosomal photodamage initiates mitochondrial-mediated apo...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Reiners, JJ, Caruso, JA, Mathieu, P, Chelladurai, B, Yin, X-M, Kessel, D
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569095/
https://ncbi.nlm.nih.gov/pubmed/12181744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.cdd.4401048
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