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Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death

Apoptosis is programmed cell death triggered by activation of death receptors or cellular stress. Activation of caspases is the hallmark of apoptosis. Arrestins are best known for their role in homologous desensitization of G protein-coupled receptors (GPCRs). Arrestins quench G protein activation b...

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Detalhes bibliográficos
Main Authors: Kook, S, Zhan, X, Cleghorn, W M, Benovic, J L, Gurevich, V V, Gurevich, E V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857626/
https://ncbi.nlm.nih.gov/pubmed/24141717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.143
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